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Drug Side Effects Are Inevitable
A new study of both computer-created and natural proteins suggests that the number of unique pockets – sites where small molecule pharmaceutical compounds can bind to proteins – is surprisingly small, meaning drug side effects may be impossible to avoid. The study also found that the fundamental biochemical processes needed for life could have been enabled by the simple physics of protein folding.
Studying a set of artificial proteins and comparing them to natural proteins, researchers at the Georgia Institute of Technology have concluded that there may be no more than about 500 unique protein pocket configurations that serve as binding sites for small molecule ligands. Therefore, the likelihood that a molecule intended for one protein target will also bind with an unintended target is significant, says Jeffrey Skolnick, a professor in the School of Biology at Georgia Tech.
Read more: http://www.laboratoryequipment.com/news/2013/05/drug-side-effects-are-inevitable
In other news the ocean is still blue
AHAHAHA NOT QUITE, OP, NOT QUITE
FUCKING NAILED IT
A+ commentary!
THANK YOU
I had seen the original making the rounds. Glad to see it got a proper rebuttal.
(Source: flowers-for-mr-ukki, via bdawg19)
Try out a cool way to separate egg yolks from egg whites!




